Gabriele Grassi Selected Research

Peptide Elongation Factors (Elongation Factor)

4/2022	High eEF1A1 Protein Levels Mark Aggressive Prostate Cancers and the In Vitro Targeting of eEF1A1 Reveals the eEF1A1-actin Complex as a New Potential Target for Therapy.
1/2020	Effects of eEF1A1 targeting by aptamer/siRNA in chronic lymphocytic leukaemia cells.
11/2019	A rapid and specific method to simultaneously quantify eukaryotic elongation factor 1A1 and A2 protein levels in cancer cells.
6/2017	Dissecting the role of the elongation factor 1A isoforms in hepatocellular carcinoma cells by liposome-mediated delivery of siRNAs.
12/2007	Overexpression of the elongation factor 1A1 relates to muscle proteolysis and proapoptotic p66(ShcA) gene transcription in hypercatabolic trauma patients.

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Gabriele Grassi Research Topics

Disease

19	Neoplasms (Cancer) 04/2022 - 04/2006
14	Hepatocellular Carcinoma (Hepatoma) 03/2022 - 08/2007
5	Inflammation (Inflammations) 01/2022 - 01/2005
4	Atherosclerosis 01/2018 - 02/2008
3	Prostatic Neoplasms (Prostate Cancer) 04/2022 - 10/2008
3	Carcinoma (Carcinomatosis) 04/2022 - 01/2020
2	Hyperplasia 04/2022 - 09/2009
2	Colorectal Neoplasms (Colorectal Cancer) 11/2019 - 06/2017
2	Ovarian Neoplasms (Ovarian Cancer) 01/2019 - 01/2019
2	Atherosclerotic Plaque (Atheroma) 01/2016 - 07/2009
2	Myocarditis (Carditis) 03/2009 - 01/2008
2	Vascular Diseases (Vascular Disease) 01/2007 - 01/2005
1	Urologic Neoplasms (Urological Cancer) 03/2022
1	Liver Cirrhosis (Hepatic Cirrhosis) 01/2022
1	Necrosis 01/2022
1	Bacterial Infections (Bacterial Infection) 01/2022
1	Cardiac Edema 12/2020
1	Leukemia 01/2020
1	B-Cell Chronic Lymphocytic Leukemia (Chronic Lymphocytic Leukemia) 01/2020
1	Hypercholesterolemia 01/2020
1	Alcoholism (Alcohol Abuse) 01/2020
1	Hypoxia (Hypoxemia) 01/2018
1	Insulin Resistance 01/2018
1	Osteoarthritis 09/2017
1	Adenocarcinoma 06/2017
1	Inflammatory Bowel Diseases (Inflammatory Bowel Disease) 06/2017
1	Interstitial Lung Diseases (Interstitial Lung Disease) 01/2017
1	Abdominal Aortic Aneurysm 06/2016
1	Thrombosis (Thrombus) 11/2012
1	Hemorrhage 11/2012
1	Cardiovascular Diseases (Cardiovascular Disease) 03/2011
1	Non-ST Elevated Myocardial Infarction 03/2011
1	Stroke (Strokes) 03/2011
1	Dilated Cardiomyopathy (Cardiomyopathy, Congestive) 03/2009
1	Infections 03/2009

Drug/Important Bio-Agent (IBA)

8	Small Interfering RNA (siRNA)IBA 03/2022 - 03/2009
7	Proteins (Proteins, Gene)FDA Link 04/2022 - 01/2007
6	Pharmaceutical PreparationsIBA 05/2020 - 12/2016
5	Peptide Elongation Factors (Elongation Factor)IBA 04/2022 - 12/2007
5	CytokinesIBA 12/2020 - 01/2005
3	Protein Isoforms (Isoforms)IBA 01/2020 - 06/2017
3	Messenger RNA (mRNA)IBA 01/2017 - 11/2007
3	Bortezomib (Velcade)FDA Link 05/2015 - 03/2009
3	CyclinsIBA 01/2014 - 08/2007
3	Matrix Metalloproteinases (MMPs)IBA 03/2011 - 06/2006
2	ParaffinIBA 04/2022 - 10/2008
2	CollagenIBA 01/2022 - 01/2008
2	Biological ProductsIBA 01/2022 - 10/2019
2	PolymersIBA 01/2022 - 03/2018
2	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 12/2020 - 12/2016
2	PlatinumIBA 05/2020 - 01/2020
2	Nucleic AcidsIBA 03/2018 - 01/2014
2	E2F1 Transcription FactorIBA 06/2017 - 01/2017
2	Proteasome InhibitorsIBA 01/2014 - 03/2009
2	Interleukin-10 (Interleukin 10)IBA 11/2007 - 01/2005
1	Formaldehyde (Formol)FDA Link 04/2022
1	Azacitidine (5 Azacytidine)FDA Link 03/2022
1	Transaminases (Aminotransferases)IBA 01/2022
1	MucinsIBA 01/2022
1	Atrial Natriuretic Factor (ANF)IBA 12/2020
1	Interleukin-6 (Interleukin 6)IBA 12/2020
1	Brain Natriuretic Peptide (Natrecor)FDA Link 12/2020
1	Hydroxymethylglutaryl-CoA Reductase Inhibitors (HMG-CoA Reductase Inhibitors)IBA 01/2020
1	Disulfiram (Antabuse)FDA Link 01/2020
1	P-2 (P 2)IBA 01/2020
1	AntibodiesIBA 11/2019
1	Cyclin D1IBA 01/2019
1	CateninsIBA 01/2019
1	Serum Amyloid A Protein (Serum Amyloid A)IBA 01/2018
1	C-Reactive ProteinIBA 01/2018
1	Fatty Acids (Saturated Fatty Acids)IBA 01/2018
1	Glutathione (Reduced Glutathione)IBA 01/2018
1	HomocysteineIBA 01/2018
1	Lipase (Acid Lipase)FDA Link 01/2018
1	HDL CholesterolIBA 01/2018
1	Glutathione Disulfide (GSSG)FDA LinkGeneric 01/2018
1	TNF-Related Apoptosis-Inducing LigandIBA 01/2018
1	Viscoelastic SubstancesIBA 09/2017
1	LubricantsIBA 09/2017
1	CelluloseIBA 08/2017
1	Liposomes (Liposome)IBA 06/2017
1	Coloring Agents (Dyes)IBA 12/2016
1	Alkaline PhosphataseIBA 12/2016
1	Metalloproteases (Metalloproteinases)IBA 06/2016
1	MicroRNAs (MicroRNA)IBA 01/2016
1	RNA (Ribonucleic Acid)IBA 08/2015
1	Biomarkers (Surrogate Marker)IBA 02/2014
1	Therapeutic UsesIBA 06/2013
1	Vitamin K Epoxide ReductasesIBA 11/2012
1	Vitamin K FDA Link 11/2012
1	omega-Chloroacetophenone (Mace)IBA 03/2011
1	Serum Response FactorIBA 05/2010

Therapy/Procedure

15	Therapeutics 04/2022 - 03/2009
3	Drug Therapy (Chemotherapy) 05/2020 - 06/2013
3	Stents 01/2016 - 08/2007
2	Precision Medicine 05/2020 - 06/2017
1	Castration 04/2022
1	Bed Rest (Bedrest) 01/2018
1	Viscosupplementation 09/2017
1	Drug-Eluting Stents 07/2009